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Dulaglutide offers weekly dosing like semaglutide but with different pharmacokinetics that some patients tolerate better
These included the phospholipid precursor PA(22:1(13Z)/19:2(10Z,13Z)), the free fatty acid Ricinoleic acid (5.1-fold), the oxidative stress marker 7-Oxo-11-dodecenoic acid, and monoacylglycerols, most notably MG(20:3(6,8,11)-OH(5)/0:0/0:0), which increased dramatically by 15.6-fold
Both are MHRA-approved, supported by large Phase 3 clinical trials, and available on prescription in the UK
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The difference matters, because the IRS has raised concerns about letters that dont reflect a real assessment
Most people adapt within 24 weeks as their body adjusts to the medication
