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However, while DPP-4 inhibitors showed an increase in such risk factors, as of 2009, no increase in pancreatic cancer has been reported in individuals taking DPP-4 inhibitors

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Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice

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Effects of anti-obesity drugs, diet, and exercise on weight-loss maintenance after a very-low-calorie diet or low-calorie diet: a systematic review and meta-analysis of randomized controlled trials

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Constipation concerns : Whilst constipation is a recognised side effect of Wegovy (reported in approximately 24% of users according to the SmPC), and chronic constipation has been theoretically linked to increased colonic pressure, there is no evidence that medication-induced constipation specifically triggers diverticulitis in those without pre-existing diverticula

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Note: Because 12.5mg exceeds the pediatric maximum dose, this strength is for adult use only [5]

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