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Retatrutide-Specific Side Effects (TRIUMPH-4, December 2025) Nausea: 38-43% (dose-dependent, mostly during step-up)

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If your period is a few days or even a couple of weeks late shortly after starting tirzepatide, hormonal adaptation may be part of the explanation

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Up to 50% of follicles shift into a rest phase, and shedding begins roughly 3 months later

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