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By taking the medication shortly before bed, some patients find that the peak nausea occurs while they are asleep, making the transition easier to handle

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6.1Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

Bang-Berthelsen CH, Holm TL, Pyke C, Simonsen L, Skilde R, Pociot F et al

A randomized clinical trial shows that only 13% of people discontinued semaglutide compared to 27.6% for liraglutide in a 68-week trial