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Thermal equilibration was then conducted for 20 ps, gradually increasing the temperature from 100 K to 298 K using the Langevin thermostat (collision frequency of 1 ps 1 )

Briefly, the radiolysis of cellular water generates highly oxidizing hydroxyl radicals which instantly abstract hydrogen atoms from the neighboring biomolecules, thus forming the alkyl radical (Fig

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The 50 mg vial is reconstituted with 2 mL of bacteriostatic water to achieve a 25 mg/mL concentration (0.25 mg per unit)

From a genomics perspective, luminal B subtype tumors show higher genomic instability and mutations (98)

Bulk RNA sequencing revealed that gene expression changes were most pronounced in the MBH, where RAMP1/3 KO mice treated with sCT showed extensive differential expression of over 1,700 genes, while WT mice exhibited comparatively minor transcriptional shifts