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Average body weight reductions of 2 kg were reported in both lixisenatide and placebo groups, reflecting a marked placebo effect in some patients receiving an inactive injection

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We illustrate this concept with an example

NOTE: A hydroxy acid exfoliator (such as Lactic Power 10) or Skin Biology Microdermabrasion Cloth can be used at opposite end of the day to improve skin cell turnover and smooth crepey areas

And in women who have obesity, this risk becomes even more clinically significant