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GWAS summary results: diabetic retinopathy
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Introduction Type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) are growing challenges worldwide, including in India, where prevalence rates are steadily rising
Known colloquially as CAROLINA (Cardiovascular Outcome Study of Linagliptin versus Glimepiride in Patients with Type 2 Diabetes), the trial is the only DPP-4 inhibitor cardiovascular outcome study with an active comparator
Future Therapeutic Directions The repeated failure of amyloid-targeted and metabolic therapies underscores the need to move beyond the amyloid cascade hypothesis and embrace alternative molecular mechanisms
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