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Ibuprofen can reduce glomerular filtration rate, particularly in patients with pre-existing chronic kidney disease, volume depletion, or heart failure

Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes

But first came John Eng, MD, a researcher at the Veterans Affairs (VA) Medical Center in the Bronx, New York, whose interest in the Gila monster a type of lizard that can slow down its metabolism and maintain stable blood sugar levels even after long periods of not eatingled to a pretty big finding

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Discussion The results of the current meta-analysis, that included 60,080 patients with T2DM, 14,804 of whom without established CV disease, demonstrate that GLP-1RA reduce the risk of MACE by 14% in the overall diabetic population, with an apparently greater effect in patients with known CV disease as compared with those without established CV disease (16% vs 6% reduction, respectively)