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Consequently, oxygen reduction uncouples from NO synthesis, transforming NOS into a proinflammatory superoxide enzyme [34]

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In detail, cyclic adenosine monophosphate (cAMP) response element-binding protein 1 (CREB1), mediated by nuclear factor erythroid 2-related factor 2 (NRF2), was reported to be essential for the maintenance of GSH dynamics in MSCs

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