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Mounjaro (tirzepatide) can cause diarrhea because it affects gut hormones that regulate how quickly and efficiently food moves through your digestive system
Science 1973, 182: 929-931
As a registered dietitian myself, I also carefully reviewed the latest research and drew on more than a decade of experience counseling patients and writing about supplements
Thirty-five-week-old MC4R mice were randomly divided into four groups with no blinding at one day before drug treatment, vehicle (saline, s.c.), semaglutide (0.5 mg/kg, s.c.), tirzepatide (0.05 mg/kg, s.c.), and retatrutide (0.05 mg/kg, s.c.) based on amounts of food intake from day 25 before drug treatment, body weight at day 2 before treatment, and fat mass at one day before treatment
Some of the rapid weight regain that occurs when people stop taking GLP-1 medications may be due to the loss of muscle, which reduces metabolism
Semaglutide-specific research A 2023 preclinical study tested semaglutide specifically in an experimental mice model of MS
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