Circulation 99 , 17131718 (1999)
More serious but less common adverse effects require clinical vigilance: Pancreatitis : Patients should be counselled to stop the medication and seek immediate medical attention if they experience severe, persistent abdominal pain radiating to the back [1] [5] Gallbladder disease : Rapid weight loss associated with GLP-1 therapy may increase cholelithiasis risk [1] Hypoglycaemia : Particularly when used alongside insulin or sulphonylureas in diabetes management Diabetic retinopathy : Semaglutide requires caution in patients with pre-existing retinopathy, who should be monitored regularly [1] Renal impairment : Dehydration from gastrointestinal side effects may affect kidney function Specific considerations for individuals with eating disorders include the potential for GLP-1 medications to exacerbate restrictive eating patterns or mask hunger cues in vulnerable individuals
References Costco
As their use expands, NPs occupy a central role in guiding appropriate prescribing, educating patients, and monitoring outcomes
He writes at the intersection of clinical medicine, health policy, and health technology, translating complex industry dynamics into sharp, evidence-based commentary for busy clinicians
For most of my patients, the side effects fade after a few weeks