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[4] Moreover, research points to a possible interaction between DSIP and opioid receptors in the brain, which may play a role in the peptides ability to regulate sleep and mitigate withdrawal symptoms, underscoring its intricate role in neural signaling pathways

The consensus is that GHK-Cu is safe compared to its alternatives

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Downregulation of Prx3 was observed in patients suffering from osteoarthritis and knock-out of this redoxin induced ferroptosis and cartilage injury in an osteoarthritis mouse model [163]