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Given that semaglutide can sometimes introduce gastrointestinal changes, the potential role of probiotics becomes particularly relevant

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A mild sulfur-like (rotten egg) taste in the mouth

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dose group (DG) 14, respectively] or 1.2 or 1.8 mg twice weekly [DG 5 and 6, respectively]), placebo or semaglutide (up to 1.0 mg qw)

In clinical trials (e.g., SURMOUNT-1), tirzepatide led to significant weight loss, an average weight loss of 15%20% of body weight over 72 weeks, when combined with diet and exercise