"This large-scale analysis suggests that OSA status may act as an effect modifier in the association between GLP-1RA prescription and mortality," Fowler said
When to pause or stop Most side effects resolve with time and do not require protocol changes
"Way back, when there really weren't too many other agents for obesity treatment," she'd prescribe more of it, she told Insider, but that was largely because "there wasn't anything else." But metformin's effects on weight loss are "kind of mild," compared to newer drugs like semaglutide, Apovian said, and persistent side effects like stomach cramps and diarrhea are a common concern among patients taking metformin
Gastroparesis is also a less common, but potentially severe side effect of GLP-1 medications
TB-500 Highlights
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