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Folic Acid. Harvard School of Public Health, 2024, National Institutes of Health
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Serious side effects include autoimmune reactions, where the body attacks organs
Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells
A metabolism-focused framework can help regulators and investigators by making the therapeutic claim testable: the product should have a defined metabolic target, a reproducible potency assay, a biologically plausible delivery window and biomarkers showing that the target changed in treated patients
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