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Cardiovascular outcome trials have established benefits for specific agents: the LEADER trial for liraglutide, SUSTAIN-6 for injectable semaglutide, and REWIND for dulaglutide demonstrated reduced risk of major adverse cardiovascular events in patients with type 2 diabetes
The interest of GLP-1 and weight loss strategies is also behavioral: by reducing the intensity of the hunger signal and the frequency of intense cravings, they can facilitate choices more consistent with a goal of sustainable weight loss
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Ann Intern Med 123 : 747753
Ideal cuando se practica actividad fsica.
NICE CKS recommends that secondary amenorrhoea lasting more than six months should prompt referral for specialist assessment
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