Incretin-based therapies (e.g., GLP-1 receptor agonists, tirzepatide, incretin, glucagon-like peptide 1, GIP agonist)
A class B receptor built for a peptide The GLP-1 receptor belongs to the class B1, or secretin, family of G-protein-coupled receptors, a group built to recognize peptide hormones rather than small molecules
A maximum penalty of 2 years imprisonment or a $9,750 fine (50 penalty units x current value of $195) is applicable
Research has shown that AOD-9604 increases the expression of beta-3 adrenergic receptors in adipose tissue, restoring suppressed receptor levels in obese models
Scientific Reports, 7
Liraglutide, semaglutide and dulaglutide have demonstrated cardiovascular benefits, and Wegovy recently added to this evidence base: in the SELECT trial, patients on Wegovy had a 20% lower incidence of heart attack, stroke or death from heart disease compared to those on a placebo