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Glutathione peroxidase 4 (GPX4), a key enzyme in lipid peroxide repair, reduces lipid peroxides by consuming GSH, thereby converting potentially toxic lipid hydroperoxides into non-toxic lipid alcohols (40)
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e574 Brown CW, Chhoy P, Mukhopadhyay D, Karner ER, Mercurio AM
Nrf2-ARE, nuclear factor erythroid 2-antioxidant responsive element
Therefore, the GSSG concentration is converted to GSH concentration by doubling the GSSG concentration
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