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investigated the synergistic effects of MSTN inhibitors and GLP-1 agonists by administering apitegromab in combination with semaglutide, a GLP-1 agonist, and tirzepatide, a dual agonist of GLP-1 and glucose-dependent insulinotropic polypeptide, in patients with obesity (NCT06445075)

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Starting at a lower dose allows your body to adapt while minimizing side effectsbut the question of whether you'll need to increase that dose depends on your individual response, genetics, and treatment goals

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