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The relationship between MOTS-c and metformin deserves careful attention
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Key questions include the onset and course of symptoms, associated symptoms (heartburn, cough, voice changes), triggers, and any weight loss or systemic complaints
PROMIS-Fatigue T -scores were also correlated with sulfated metabolites of androgen including androstenediol (3beta,17beta) monosulfate ( r = 0.26, p = 0.0008), 5alpha-androstan-3beta,17beta-diol disulfate ( r = 0.21, p = 0.0083), 5alpha-androstan-3beta,17beta-diol monosulfate ( r = 0.20, p = 0.012), 5alpha-androstan-3alpha,17alpha-diol monosulfate ( r = 0.22, p = 0.0062), and 5alpha-androstan-3beta,17alpha-diol disulfate ( r = 0.17, p = 0.028) (Figure 5)
It also helps improve skin elasticity and clarity, giving the skin a more youthful and radiant appearance
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