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Theres a rationale behind localized injection: some practitioners use it near a specific treatment area on the theory that proximity might concentrate effects locally

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There is a possibility of hemolytic anemia of the fetus/newborn due to immature erythrocyte enzyme systems (glutathione instability)

Link SL, Rampon G, Osmon S, Scalzo AJ, Rumack BH

A randomized-controlled, double-blind study of the impact of selenium supplementation on thyroid autoimmunity and inflammation with focus on the GPx1 genotypes