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(2) mechanistic studies to determine biological plausibility
Primarily, there is a significant deficit of human studies evaluating functional aging outcomes rather than just common metabolic indicators, which should include assessments of cognitive ability, physical performance, and physiological resilience
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Hims & Hers Health: The GLP-1 Trade Just Got Real (Rating Downgrade) Summary Downgrading Hims & Hers Health, Inc
A 2026 systematic review in the European Journal of Endocrinology found GLP-1 receptor agonists were associated with modest short-term weight loss in women with PCOS and overweight or obesity
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