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TB-500 refers specifically to a synthetic fragment (residues 1723, sequence Ac-LKKTETQ) containing the core actin-interacting motif
Ethics declarations Ethics approval and consent to participate The animal study was reviewed and approved by Experimental Animal Center of Wenzhou Medical University (Approval ID: wydw2022-0032)
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While modulation of the GSH-antioxidant system has provided promising preclinical results, some of these compounds demonstrate unacceptable toxicity profiles (eg, buthionine sulfoximine)
No universal success rate data exists
Standard Maintenance Dose The usual dose for Vitamin B12 injections is 1,000 mcg every month
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