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Interestingly, GCGR-deficient mice are resistant to streptozotocin (STZ)-induced beta cell destruction and hyperglycaemia [111], which led to the suggestion that the presence of glucagon might be more important for the hyperglycaemia associated with type 1 diabetes than the lack of insulin [13]

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Based on clinical trial data from Novo Nordisk, people who took the pill along with maintaining a reduced-calorie diet and increased physical activity lost an average of 13% of their body weight over 64 weeks

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Ma QL, Yang F, Rosario ER, Ubeda OJ, Beech W, Gant DJ, et al