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The subsequent increase in metabolic rate leads to a reduction in white adipose tissue and has been shown to produce significant weight loss in preclinical studies without affecting appetite
GLP-1 and GIP receptor agonists have a low intrinsic risk of causing hypoglycaemia when used alone, because their insulin-stimulating effects are glucose-dependent
Comparison Both work on fat metabolism
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Higher doses (particularly 54 mg) showed somewhat increased gastrointestinal symptoms compared to lower doses
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