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We present a case of ischemic colitis in a young woman with no significant comorbidities, raising concern for a potential drug-related complication

Similarly, ONCOS-102, an engineered adenovirus expressing GM-CSF, has been tested with pembrolizumab in advanced melanoma (NCT03003676), aiming to activate dendritic cells and potentiate T-cellmediated responses

These help to defend the skin from environmental stressors

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