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10: STEP THERAPY NOT FOLLOWED An insurance payer may require the use of a preferred drug for intravitreal injections, typically a lower-cost medication such as bevacizumab, before initiating treatment with a higher-cost drug such as aflibercept

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In a notable phase II clinical trial published in The Lancet (2008), Tesofensine demonstrated dose-dependent weight loss of up to 10.6% over 24 weeks in obese individualssubstantially higher than placebo or many existing weight-loss drugs

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