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Amylin, released with insulin from beta cells in the pancreas, induces its satiating effect via both the homoeostatic and hedonic regions of the brain
Results Patients lose an average of 10-15% of body weight over 68 weeks in registration trials for FDA-approved formulations
Spray and swallow
The goal is to let the hypothalamic-pituitary axis adjust gradually
Investigating root causes If two different incretin-based medications have failed, the problem may not be the medications
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