glp 1 review Frontiers Current Insights, Advantages and Challenges

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W., Miller, J

A useful comparison point is the acylation chemistry described for semaglutide by Lau and colleagues in the Journal of Medicinal Chemistry in 2015 [2], which introduced a C18 diacid linked through a spacer to achieve albumin binding on a GLP-1 scaffold

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Data availability Data generated and analyzed in this study are included in the paper and the Supporting Information (supplementary Figures 1-7 and legends), and are also available to interested person from the corresponding author upon reasonable request