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Therefore, it could be considered as a promising adjuvant in the treatment of diabetes and its complications
PMID:25504085
SOCS1 can reduce the expression of SLC7A11, in addition to GSH levels, sensitizing cells to ferroptosis (Saint-Germain et al., 2017)
For reference, the pivotal trials enrolled adults with a body mass index of 30 kg/m or greater, or 27 kg/m or greater with at least one weight-related comorbid condition such as treated or untreated dyslipidemia or hypertension
In the U.S., about 6% of adults currently use GLP-1s, and 12% have used them in the past (2024 data) (Mozafariun 2025)
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