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A recent study further revealed that TIMM17B may impact ferroptosis and chemotherapy resistance in breast cancer through its effect on GPX4 ( Studies have demonstrated that erastin significantly enhances the chemotherapeutic efficacy of temozolomide, cisplatin, cytarabine, and doxorubicin by inducing ferroptosis ( 3 Ferroptosis-related drug resistance in different subtypes of breast cancer Chemotherapy is a critical therapeutic strategy for breast cancer, which remains a complex process involving multiple genes and signaling pathways

The erasers comprise FTO and ALKBH5, which catalyze -ketoglutarate- and Fe 2 -dependent oxidative demethylation

Abstract Neem, called Arista in Sanskrit, meaning reliever of sickness, often referred to as the bitter gem, is one of the most celebrated plants in the Indian Traditional Healthcare system for its diverse medicinal properties

Wang Y, Chen CZ, Fu XH, Liu JB, Peng YX, Wang YJ, et al

Rukmini Rednam