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Most compounding pharmacies assign a beyond-use date (BUD) of 28 to 90 days from compounding for refrigerated vials
However, high doses of vitamin B12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Its important to note that these side effects are generally mild and temporary
Perhaps most notably, the researchers observed no adverse effects even at high doses
This can lead to a feeling of exhaustion even after adequate rest
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