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8 Future directions Conventional antioxidants face limitations in efficacy and specificity, but emerging strategiesincluding mitochondria-targeted compounds and Nrf2 activatorsaddress these challenges through three transformative mechanisms: Precision targeting Unlike broad-acting scavengers, these agents accumulate within mitochondria, the primary source of ROS
For many individuals it can be one or more servings, one, two, three or more times per day
218 L Lactic acid, a product of glycolysis, can upregulate the expression of the ferroptosis-related proteins GPX4 and FSP1 and increase the levels of NADH, NADPH, and GSH, thereby inhibiting ferroptosis
10.1016/bs.apha.2019.01.006 43 IorgaA.DaraL.KaplowitzN
IV Glutathione vs Oral Supplements Which One Is More Effective
Sep 1 2022;19(3)doi:10.1515/jib-2022-0004
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