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In silico examination of CBS promoter by Jaspar software 38 predicted one putative antioxidant response element (ARE) ~ 5 kb upstream of the transcription start site, which is highly associated with H3K4Me1, H3K4Me2, H3K4Me3, and H3K9Ac histone marks (Supplementary Fig

Worthy of mention, a rise in the prevalence of subclinical autoimmune hypothyroidism and thyroid autoantibodies has been reported after iodine supplementation in iodine-deficient countries, likely in relation to enhanced immunogenicity of thyroglobulin [27]

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The oral glutathione supplement was slightly beneficial for skin lightening in particular subgroups, but the results were not statistically significant

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This narrower focus often aligns with stronger quality signals and more transparent verification practices.