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A meta-analysis of 6 studies 13,20,30,32,33,35 which attempted to estimate overall effect size of the changes from baseline in % FMD following GLP-1-based therapies could not find any significant difference between baseline and end-of-treatment samples (mean change from baseline was 0.83 [1.06, 2.73] %

Journal of Clinical and Translational Science , 7 (1), e184

IUBMB Life 71 , 969977 (2019)

During unusual circumstances, such as the COVID-19 pandemic, the approach to managing chronic conditions like pernicious anaemia, which requires regular B12 injections, had to be adapted, potentially influencing the perception of efficacy and safety of the treatment among patients

This confirms that when dry mouth does occur, it is mild and goes away

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