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In atherosclerotic rats, trimetazidine (30 mg/kg/day for 12 weeks) prevented ROS upregulation, and restored antioxidant SOD levels while reducing oxidized low-density lipoprotein and malondialdehyde [169]
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This deficiency can lead to various issues such as nervous problems and anaemia
While we need methionine and protein in the diet, one way to increase homocysteine is to significantly increase dietary methionine without a concomitant increase in choline, B12, or folate.[ref] Timing of testing: Homocysteine levels are lowest in the first hour after a meal, so if you test your homocysteine level after eating, it will likely be different than what a fasting blood test will show.[ref] Down syndrome, CBS, and low homocysteine: People with Down syndrome usually have very low homocysteine levels due to the extra copy of chromosome 21, which causes an extra copy of the CBS gene
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