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Adverse effects are rare and mild
The active site lysine abstracts a proton during the second half of the reaction, leading to the formation of ribulose 5-phosphate
Acute Liver Failure Study Group found that acetaminophen poisoning was the cause of acute liver failure in 18% of cases initially judged to be of unknown cause
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Most researchers find Saturday or Sunday administration convenient since any GI adjustment during the first 24 to 48 hours post-injection aligns with time away from work demands
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