However, due to limited study and potential adverse effects, its use for this purpose is neither generally accepted nor advised
PubMed Central , Brain, Behavior, and Immunity , vol
In particular, it was hypothesized that an altered metabolism of folate, resulting from the presence of polymorphisms in metabolic genes, could lead to aberrant methylation of peri-centromeric regions of chromosome 21, favoring its abnormal segregation during maternal meiosis and leading to the formation of eggs with two copies of chromosome 21, which, if fertilized, would result in a zygote with full trisomy for chromosome 21 (James et al., 1999
DykaDRodzeRodzeMPacholak-KlimasAEdeGSethiSet al
Start with the recommended dosage, stay hydrated, and adjust as needed
Selectively stimulates the release of endogenous growth hormone