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Kidney function was evaluated using the urea assay kit (Beyotime, S0574) and the Amplex Red creatinine assay kit (Beyotime, S0291)
Selenium status becomes rate-limiting: targeting plasma selenium of 120150 g/L through selenomethionine 200 g/day is more effective in these carriers than in wild-type individuals
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As a result, regular monitoring of liver enzymes (ALT) is recommended for patients on long-term tolvaptan therapy [104]
Another mechanism may be the anti-inflammatory effect of KD
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