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In short, Nooms individualized approach to titration can optimize the riskbenefit tradeoff , which can be especially important for patients at higher risk of discontinuation
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It can be used as monotherapy when metformin is inappropriate, or in combination with other glucose-lowering medicinal products, including insulin, when these alone are inadequate
Berberine should be avoided or used only under medical supervision in the following groups: Pregnant or breastfeeding women Children and adolescents Individuals with liver or kidney impairment Those taking multiple prescription medicines, particularly narrow therapeutic index drugs People with a history of hypoglycaemia or taking glucose-lowering medicines Anyone taking warfarin, digoxin, ciclosporin, or tacrolimus If you are unsure whether berberine is appropriate for you, your GP or a registered pharmacist is the most appropriate first point of contact
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Reference: #MedicalAffairs #GLP1 #ObesityManagement #ClinicalTrials #CardiovascularRisk #EvidenceBasedMedicine #LifeSciences #Pharma To view or add a comment, sign in Hydroxychloroquine vs Teneligliptin in Uncontrolled Type 2 Diabetes A Randomized Trial Introduction Managing Type 2 diabetes mellitus (T2DM) becomes increasingly complex when patients remain inadequately controlled despite combination therapy with metformin, glimepiride, and insulin
