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Start at a low dose of 3 mg daily and increase the dosage after 4 weeks or 30 days, as prescribed by your healthcare provider

doi: 10.9778/cmajo.20200231 8 GreenVLinJMcGrathMLloydAMaPHigaKet al

Last reviewed: July 21, 2026 Last updated: July 21, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

At baseline, SURPASS-1 participants had the lowest SBP and duration of diabetes (127.6 mmHg and 5 years) compared to SURPASS-5 participants (137.9 mmHg and 13 years)

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Its role in the management of type 2 diabetes and obesity is increasingly prominent, reflecting its importance in personalized medicine and patient-centered care