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Rizvi, Incretin-Based, Therapies, Glucometabolic Health and Endovascular Inflammation

PRKCSH encodes for a protein called hepatocystin or 80K-H, which is a beta subunit of glucosidase II 26 and substrate for protein kinase C 26 , that plays a key role in GLUT4 vesicle trafficking (translocation of GLUT4 to the plasma membrane) in the insulin signaling pathway 72 by forming a complex with 80K-H Overexpression of the hepatocystin 1 week after 4-week intermittent fasting is suggestive of improvement of insulin signaling through enhancement of GLUT4 vesicle trafficking

132 NakagawaT.ShimizuS.WatanabeT.YamaguchiO.OtsuK.YamagataH.et al (2005)

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Selenium deficiency stimulated the expression of the chondrocyte hypertrophy marker gene type X collagen in the articular cartilage (116)