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The model was first fitted to the training concentrations (37.5 and 25 M doxorubicin), and then used to simulate the test concentrations (50, 12.5 and 10 M doxorubicin) as a means of blind validation, showing good accordance between the experimental and in silico outputs for all concentrations of doxorubicin

Wegovy for weight management), dulaglutide (Trulicity), liraglutide (Victoza for diabetes

Tapper EB, Parikh ND, Waljee AK, et al

Gastroenterology 122:531544 Drucker DJ, Yusta B, Boushey RP et al (1999) Human [Gly2]GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis

HFpEF is especially associated with age as well as female sex and conditions such as diabetes, obesity, hypertension, coronary heart disease and CKD

Guptarak J, Scaduto P, Tumurbaatar B et al (2024) Cognitive integrity in Non-Demented Individuals with Alzheimers Neuropathology is associated with preservation and remodeling of dendritic spines