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This is especially relevant for GLP-1 users who report feeling like the stool is right there but will not come out, or who experience excessive straining despite having soft stool
As a result, womenespecially in midlifewere routinely excluded from trials, and clinical guidance lagged behind lived reality
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doi: 10.1016/j.celrep.2018.03.070 280 ChuAYWorkalemahuTPaynterNPRoseLMGiulianiniFTanakaTet al
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