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In February 2025, the FDA declared that the shortage was over
Clinical data from weight-loss medication trials shows that patients drinking at least 2.53 liters (1012 cups) daily experience constipation rates 40% lower than those drinking less than 1.5 liters
Unlike brand-name medications, compounded GLP-1 formulations from licensed 503A pharmacies allow providers flexibility in dosing and delivery methods
Out-of-state pharmacies shipping into Florida need Florida non-resident pharmacy registration
The IGF-1 axis benefits from the same pause: it drifts back toward baseline instead of sitting chronically elevated, which is the safer position given GH/IGF-1s growth-promoting signaling
Diabetic eye disease (retinopathy) Fast improvements in blood sugar control may lead to a temporary worsening of diabetic eye disease
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