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Currently there are 7 clinical trials registered for the use of itraconazole as a combinatory therapy in ovarian cancer patients and 6 in breast cancer patients (clinicaltrials.cov)
They also have harmful effects on embryo development (Pietrzik and Bronstrup, 1997
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Animal toxicology data from Sikiric's group showed no LD50 (median lethal dose) could be established in rats, suggesting a wide therapeutic index 31
Mokhtari V, Afsharian P, Shahhoseini M, Kalantar SM, Moini A
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