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The body receives a flat dose, processes it, and the negative feedback loop eventually suppresses endogenous production

These macrophages secrete pro-inflammatory cytokines such as IL-1 and TNF-, which not only promote intra-articular inflammation but also directly contribute to the degradation of the cartilage matrix (85, 137, 138)

10.1016/j.ecoenv.2019.109840 28 ElsedawiB

Chronic conditions require sustained management rather than acute intervention

Used in several sessions, it significantly improves the appearance of the skin

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