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Besides GLPs, DPP-IV is able to cleave some chemokines and cytokines such as IL-3, and granulocyte-macrophage colony-stimulating factor (GM-CSF), thereby regulating the immune responses (Kameoka et al

Bariatric surgery involves surgical risks, while GLP-1 medications are more commonly associated with digestive side effects and nutrition-related challenges

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While a negative feedback loop has not been identified, the very high levels of these medications not only flood the body, but do so for extended periods, unlike endogenous GLP-1, which normally fluctuates in response to eating

The published literature on GLP-1 agonists in pediatrics is predominantly from pediatric patients 10-18 years old

If lost weight, drink up the difference with water and electrolytes