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Glucose dysregulation
The dry powder takes up about 60% of the volume of the vial
Phosphoinositide-3-kinase The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) is an intracellular pathway involved in the regulation of a variety of critical cellular physiological processes involved in the cell cycle growth and proliferation and apoptosis, protein synthesis, and drug resistance in response to stimulation by growth factors, cytokines and hormones (Leslie and Downes 2002)
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Delgado-Esteban M, Almeida A, Bolanos JP
One prominent mechanism is the downregulation of major histocompatibility complex class I (MHC-I) molecules on tumor cells, which impairs antigen presentation and reduces the visibility of malignant cells to cytotoxic T lymphocytes (36)
