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App NL-G-F mouse also exhibited inflammatory events similar to GCLC-KO mouse

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Research efforts expanded throughout the 1990s and 2000s as investigators explored the peptide's potential influence on tissue repair, angiogenesis, and gastrointestinal integrity

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Experimental investigations have reported interactions with VEGFR2 phosphorylation, focal adhesion kinase (FAK) activation, ERK1/2 signaling, nitric oxide-associated pathways, and extracellular matrix regulatory networks